A 23kD molecule of Plasmodium falciparum binds specific IgG from splenomegalic, parasitemic, but asymptomatic children. A pilot study in a malarious community in Palawan, The Philippines.
-
- TONGOL-RIVERA PILARITA
- Department of Parasitology, Gunma University School of Medicine Department of Parasitology, College of Public Health, University of the Philippines Manila
-
- KANO SHIGEYUKI
- Department of Parasitology, Gunma University School of Medicine
-
- CANETE-MIGUEL EDITHA
- Palawan Provincial Hospital
-
- SUZUKI MAMORU
- Department of Parasitology, Gunma University School of Medicine
書誌事項
- タイトル別名
-
- 23kD Molecule of Plasmodium falciparum
- A PILOT STUDY IN A MALARIOUS COMMUNITY IN PALAWAN, THE PHILIPPINES
この論文をさがす
抄録
A pilot sero-epidemiological study was performed in Palawan, The Philippines, in a community within which annual malarial transmission takes place. Sera obtained from splenomegalic and asymptomatic children with current falciparum infection (Group I) were examined using a Western blotting technique to determine the reactivity to electrophoresed antigenic molecules of Plasmodium falciparum (P.f.) . Group I sera consistently exhibited specific reactivity of IgG to a 23kD molecule, to which sera obtained from another group of asymptomatic children with neither parasitemia nor splenomegaly (Group II) exhibited no distinct reactivity. A 58kD molecule was also exhibited by the Group I sera, while several Group II sera reacted with a 52 kD molecule in association with the 47kD which was reported to be indicative of present and/or recent past clinical episode of falciparum infection. Determination of the immunological features of the antigenic molecules of parasites by this type of sero-epidemiological study will provide a new assay system for evaluation of immune status in communities endemic for malaria.
収録刊行物
-
- Japanese Journal of Tropical Medicine and Hygiene
-
Japanese Journal of Tropical Medicine and Hygiene 25 (1), 1-5, 1997
日本熱帯医学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001204951786368
-
- NII論文ID
- 130003975935
- 10011490759
-
- NII書誌ID
- AN00196023
-
- ISSN
- 21861781
- 21861811
- 03042146
-
- NDL書誌ID
- 4174562
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可