書誌事項
- タイトル別名
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- Cytogenetic Study of Essential Thrombocythemia
- ホンタイセイ ケッショウバン ケッショウ ノ サイボウ イデンガクテキ ケンキ
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抄録
Cytogenetic studies were performed on the bone marrow (BM) cells obtained from 12 patients with essential thrombocythemia (ET). Two of them had chromosome abnormalities. One patient showed a mosaic of two karyotypes of 46, XY and 46, XY, -15, del (6) (q25), +der (15) t (15; ?) (q26; ?). This abnormal karyotype was observed in half of the checked BM metaphases. The other patient showed only one karyotype of 46, XY, del (20) (q11) in the BM. In both of patients, chromosomal analyses on the cultured peripheral blood cells with phythohemagglutinin (PHA) for 72 hrs were carried out and all metaphases observed were normal male karyotypes. The frequency of polyploid cells was less than 1% in all cases except one with 3.3%. No relationship between cytogenetic findings and clinical manifestations or results of another clinical examinations was observed.
収録刊行物
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- 臨床血液
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臨床血液 28 (4), 529-533, 1987
一般社団法人 日本血液学会
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詳細情報 詳細情報について
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- CRID
- 1390001205030962432
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- NII論文ID
- 130004918522
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- NII書誌ID
- AN00252940
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- COI
- 1:STN:280:BiiA3M3itVI%3D
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- ISSN
- 18820824
- 04851439
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- NDL書誌ID
- 3136606
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- PubMed
- 3626045
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可