播種性血管内凝固症候群(DIC)準備状態に関する検討

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書誌事項

タイトル別名
  • Coagulation Study before Oncet of Disseminated Intravascular Coagulation
  • ハシュセイ ケッカンナイ ギョウコ ショウコウグン DIC ジュンビ ジョウタ

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説明

We performed blood coagulation studies in 50 patients within a week before onset of disseminated intravascular coagulation (DIC).<br>Since two peaks were observed for the onset, it was suspected that DIC was composed of acute and chronic types. The DIC score before onset was 4.9±1.2 in the non-leukemic group and 2.4±0.8 in the leukemic group.<br>Prekallikrein activity, FDP, fibrinogen and platelet number were frequently abnormal, but PT and antithrombin III weré slightly abnormal in the non-leukemic group.<br>Although the incidence of abnormal finding was lower in the leukemia group than in the non-leukemia group, the data on the leukemia group were similar to those on the non-leukemic group and elevated D-dimer level and decreased platelet count were particularly frequent in the leukemic group. The incidence of abnormal data in all patients was 44±14%.<br>Abnormalities of blood coagulation were observed within a week before the onset of DIC, and prekallikrein activity, platelet number, FDP and D-dimer might be useful for diagnosis of Pre-DIC state.

収録刊行物

  • 臨床血液

    臨床血液 29 (11), 2011-2017, 1988

    一般社団法人 日本血液学会

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