書誌事項
- タイトル別名
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- A case of patient with complete remission from atypical aplastic anemia by betamethasone therapy, whose peripheral lymphocytes suppressed granulocytic colony formation (CFU-C) of normal bone marrow cells
- 患者リンパ球にCFU-C抑制作用を認め,betamethasoneが著効を呈した非定型的aplastic anemiaの1例
- カンジャ リンパキュウ ニ CFU-C ヨクセイ サヨウ オ ミトメ beta
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抄録
Up to the present, the pathogenesis of aplastic anemia has been discussed by many investigators, but it still remains in dispute. Lately in some cases of aplastic anemia the suppression to bone marrow stem cells through immunological mechanism was suspected for the ca use of this disease.<br>In the present report, we describe a young male patient of atypical aplastic anemia, whose peripheral lymphocytes suppressed a colony forming unit (CFU-C) of normal marrow cells.<br>Although the anabolic steroid was proved to be ineffective, complete remission was brought by the treatment with a high dose of betamethasone.<br>It was therefore assumed that in this patient the circulating lymphocyte was playing a pathognomonic role for aplastic anemia by their suppressive activity on the proliferation of bone marrow cells.
収録刊行物
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- 臨床血液
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臨床血液 23 (3), 385-391, 1982
一般社団法人 日本血液学会
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詳細情報 詳細情報について
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- CRID
- 1390001205032762368
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- NII論文ID
- 130004498435
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- NII書誌ID
- AN00252940
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- COI
- 1:STN:280:Bi2B28bls1U%3D
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- ISSN
- 18820824
- 04851439
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- NDL書誌ID
- 2486755
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- PubMed
- 7109235
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可