突然卵巣出血で死亡したvon Willebrand病の1剖検例

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書誌事項

タイトル別名
  • An autopsy case of von Willebrand's disease died of sudden ovarial hemorrhage
  • トツゼン ランソウ シュッケツ デ シボウ シタ von Willebrandビョウ ノ 1 ボウケンレイ

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説明

A case of twenty three years old female with hemorrhagic diathesis was diagnosed as von Willebrand's disease in 1967.<br>Bleeding time was 25 minutes, coagulation time, platelet counts and clot retraction were normal, and rate of platelet adhesiveness was 11%.<br>Factor VIII activity was elevated from 5% to 25% after an infusion of AHG concentrate (Cohn fraction I), although the logically expected value was estimated to be 14%.<br>After two and half years of her dismissal from the hospital, she complained of sudden severe abdominal pain and thereafter her vital signs were diminished markedly, and she died on the next day. At autopsy, there was 1000 ml of blood in the abdominal cavity, and some hematomas were found in the bilateral ovaries and retroperitoneal serosa.<br>The massive ovarial hemorrhage probably due to the ovulation seemed to be the direct cause of her death.

収録刊行物

  • 臨床血液

    臨床血液 12 (3), 261-265, 1971

    一般社団法人 日本血液学会

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