スパックフェリチンキットの基礎的ならびに臨床的研究

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書誌事項

タイトル別名
  • Basic and Clinical Studies on SPAC Ferritin Kit
  • スパックフェリチンキット ノ キソテキ ナラビニ リンショウテキ ケンキュウ

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説明

Kit for serum ferritin assay (SPAC ferritin kit) which was offered by Daiichi Radioisotope Labs. was studied on the basic points and serum ferritin was measured in various hematological diseases. Concerning to the basic points, a reproducibility test, a recovery test and a dilution test were examined. From these results, a good correlation was obtained in each test, however, when the values showed more than 150∼200 ng/ml, a proper dilution and a reexamination should be recommended because of an increasing error.<br>Concerning to the clinical examinations, sera form the normal subjects and the patients with hematological diseases, for example, iron deficiency anemia, aplastic anemia, hemolytic anemia, polycythemia vera, leukemia, multiple myeloma, myelofibrosis and so on were examied. In normal subjects, a significantly higher value in men was shown than in woman. Iron deficiency anemia showed a markedly low value and serum ferritin elevated after an effective treatment. In other hematological dieases, serum ferritin showed various values. Based on these results, it was suggested that they may reflect an iron deficiency state due to a bleeding, a disturbed iron utilization due to an impaired erythropoiesis, an iron overload state due to blood transfusions, a production by leukemia cells, a release from liver cells and so on.

収録刊行物

  • 臨床血液

    臨床血液 21 (3), 308-319, 1980

    一般社団法人 日本血液学会

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