Effects of Anti-Anginal Agents on Cyclical Reductions of Coronary Blood Flow
-
- UCHIDA Yasumi
- Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
-
- YOSHIMOTO Nobuo
- Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
-
- MURAO Satoru
- Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
書誌事項
- タイトル別名
-
- Effects of Anti Anginal Agents on Cycli
この論文をさがす
抄録
The effects of coronary vasodilating agents and alpha- and beta-adrenergic blocking agents on cyclical reductions of blood flow in the partially constricted coronary artery of anesthetized dogs were examined. Intravenous injections of nitroglycerin (50μg/Kg), SG 75 (150μg/Kg), papaverine (1mg/Kg), and nicotinic acid (10mg/Kg) eliminated both cyclical reductions of flow and ST elevation (group 1). Nifedipine (10μg/Kg), verapamil (500μg/Kg), diltiazem (500μg/Kg), and propranolol (500μg/Kg) suppressed ST elevation, but they could not eliminate cyclical reductions of flow (group 2). Dipyridamole (1mg/Kg) and phentolamine (500μg/Kg) augmented both ST elevation and cyclical reductions of flow (group 3). The results indicate that ST elevation due to cyclical reductions of coronary blood flow was eliminated by spasmolytic actions of group 1 on coronary artery, was suppressed by negative chronotropic and/ or inotropic actions of group 2, and was augmented by peripheral actions of group 3.
収録刊行物
-
- Japanese Heart Journal
-
Japanese Heart Journal 19 (6), 904-912, 1978
International Heart Journal刊行会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001205038224000
-
- NII論文ID
- 130000762464
-
- NII書誌ID
- AA00690786
-
- COI
- 1:CAS:528:DyaE1MXltFOgs7w%3D
-
- ISSN
- 1348673X
- 00214868
-
- NDL書誌ID
- 2074109
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可