SOLITARY FIBROUS TUMOR PRESENTING AS PERIVESICAL MASS ASSOCIATED WITH HYPOGLYCEMIA: A CASE REPORT

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  • 低血糖を併発した perivesical solitary fibrous tumor の1例
  • 症例報告 低血糖を併発したperivesical solitary fibrous tumorの1例
  • ショウレイ ホウコク テイケットウ オ ヘイハツ シタ perivesical solitary fibrous tumor ノ 1レイ

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Some non-islet tumors can induce hypoglycemia. We report a case of a solitary fibrous tumor (SFT) as perivesical mass associated with hypoglycemia. A 61-year-old man was admitted to our department with recurrent hypoglycemic attack and lower abdominal discomfort, but no symptom of urination. Ultrasonography and magnetic resonance imaging demonstrated a giant heterogeneous mass in the pelvic and rightward shift of bladder, but the tumor's border was clear. Endocrinological analyses showed high serum levels of insulin-like growth factor II (IGF-II) and suppressed secretion of insulin. We removed perivesical tumor that weighted 720g on 30th January in 2003. After the removal, serum IGF-II levels returned to normal and hypoglycemic attacks ceased. Pathological examination revealed well-circumscribed nodular mass composed of uniform spindle cells arranged in bundles and fascicles with varying amounts of collagen and reticulin fibers. Almost all of the tumor cells were immunohystochemically positive for vimenntin and CD34, negative for cytokeratin.

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