A Case of Alcoholic Ketoacidosis Accompanied with Severe Hypoglycemia

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  • MATSUZAKI Tadanobu
    Department of neurology, JCHO (Japan Community Health care Organization) Kyushu Hospital
  • SHIRAISHI Wataru
    Department of neurology, JCHO (Japan Community Health care Organization) Kyushu Hospital
  • IWANAGA Yasutaka
    Department of neurology, JCHO (Japan Community Health care Organization) Kyushu Hospital
  • YAMAMOTO Akifumi
    Department of neurology, JCHO (Japan Community Health care Organization) Kyushu Hospital

Bibliographic Information

Other Title
  • アルコール性ケトアシドーシスの急性期に著明な低血糖を呈した1例
  • 症例報告 アルコール性ケトアシドーシスの急性期に著明な低血糖を呈した1例
  • ショウレイ ホウコク アルコールセイ ケトアシドーシス ノ キュウセイキ ニ チョメイ ナ テイケットウ オ テイシタ 1レイ

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Description

We report a 55 year old Japanese man with a history of alcohol abuse, who was in a near fasting state for the previous few days.He was admitted to our hospital with abrupt disturbance of consciousness. He presented disturbance of consciousness with extreme hypoglycemia and ketoacidosis with high β-hydroxybutyric acid concentration. Taking into account his living history, we diagnosed with alcoholic ketoacidosis (AKA). Symptoms ameliorated with glucose injection and fluid loading. AKA patients show abdominal pain, nausea or vomiting, but they are usually alert and lucid despite the severe acidosis. This case, however, presented comatose status caused by hypoglycemia. Poor oral intake of this patient was assumed to be the cause of hypoglycemia. Alcoholism may cause hypoglycemia accompanying with AKA, due to a low carbohydrate intake, the inhibition of gluconeogenesis, and reduced hepaticglycogen storage as seen in this case. Here, we report a case of AKA that demonstrated hypoglycemia with the literature review.

Journal

  • Journal of UOEH

    Journal of UOEH 37 (1), 43-47, 2015-03-01

    University of Occupational and Environmental Health, Japan

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