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- 上田 実
- 名古屋大学大学院医学研究科頭頸部感覚器外科学講座
書誌事項
- タイトル別名
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- Bone regeneration using osteogenic stem cell and sonic hedgehog gene
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In this article the general strategy for bone regeneration using osteogenic stem cell and gene modified cells. In the past autogenous bone grafting was the most reliable and well documented technique for bone regeneration. However the patient usually is demanded the heavy burden for harvesting the grafted bone in the donor sites. In this circumstances the tissue engineering concept has been developed and introduced for clinical use.<BR>In this article the general strategy for bone regeneration using tissue engineering concept. We have tried two essential elements such as mesenchymal stem cell and sonic hedgehog gene to generate the bone tissue.<BR>Marrow expanded mesenchymal stem cell with ceramics scaffold have been studied and confirmed its usability for bone engineering especially for cavitary bone defects in the jaw bone. Also the sonic hedgehog gene modified fibroblasts could be useful for the systemic bone disease such as osteoporosis.
収録刊行物
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- 炎症・再生
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炎症・再生 23 (5), 262-268, 2003
一般社団法人 日本炎症・再生医学会
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詳細情報 詳細情報について
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- CRID
- 1390001205179209984
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- NII論文ID
- 130000165320
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- NII書誌ID
- AA11508953
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- ISSN
- 18805795
- 13468022
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可