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- TEH Lay Kek
- Pharmacogenomics Centre (PROMISE), Faculty of Pharmacy, Universiti Teknologi MARA
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- BERTILSSON Leif
- Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University, Hospital-Huddinge, Karolinska Institutet
書誌事項
- タイトル別名
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- Pharmacogenomics of CYP2D6: Molecular Genetics, Interethnic Differences and Clinical Importance
この論文をさがす
説明
CYP2D6 has received intense attention since the beginning of the pharmacogenetic era in the 1970s. This is because of its involvement in the metabolism of more than 25% of the marketed drugs, the large geographical and inter-ethnic differences in the genetic polymorphism and possible drug-induced toxicity. Many interesting reviews have been published on CYP2D6 and this review aims to reinstate the importance of the genetic polymorphism of CYP2D6 in different populations as well as some clinical implications and important drug interactions.<br>
収録刊行物
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- Ｄｒｕｇ Ｍｅｔａｂｏｌｉｓｍ ａｎｄ Ｐｈａｒｍａｃｏｋｉｎｅｔｉｃｓ
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Ｄｒｕｇ Ｍｅｔａｂｏｌｉｓｍ ａｎｄ Ｐｈａｒｍａｃｏｋｉｎｅｔｉｃｓ 27 (1), 55-67, 2012
日本薬物動態学会
