Antibacterial activities of extracts and constituents in the rhizomes of diploid and tetraploid gingers (<i>Zingiber officinale</i> Roscoe)

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  • 二倍体及び四倍体ショウガの抽出エキス及び化合物の抗菌活性
  • Antibacterial activities of extracts and constituents in the rhizomes of diploid and tetraploid gingers (Zingiber officinale Roscoe)

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Abstract

The pungent phenolics were isolated from the rhizome of tetraploid ginger (Zingiber officinale Roscoe), and their structures were established as [6]-gingerol and [6]-dehydroparadol by chemical and spectroscopic evidence. And extracts and constituents in the rhizomes of diploid and tetraploid gingers were screened for their antibacterial activity against 6 Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Salmonella enteritidis, Vibrio parahaemolyticus, and Yersinia enterocolitica) and 3 Gram-positive bacteria (Staphylococcus aureus, Listeria monocytogenes, and Bacillus cereus). The minimum inhibitory concentrations (MICs) of extracts and constituents in the rhizomes were determined by the microdilution method ranged from 0.49 to 16,000μg/ml, and 0.03 to 1,000μg/ml, respectively. Extracts and constituents in the rhizomes exhibited a fairly high antibacterial activity against the spectrum of most Gram-positive bacteria tested.

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