Effects of Pyridalyl, a Novel Insecticidal Agent, on Cultured Sf9 Cells
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- Saito Shigeru
- Agricultural Chemicals Research Laboratory, Sumitomo Chemical Co., Ltd.
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- Sakamoto Noriyasu
- Agricultural Chemicals Research Laboratory, Sumitomo Chemical Co., Ltd.
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- Umeda Kimitoshi
- Agricultural Chemicals Research Laboratory, Sumitomo Chemical Co., Ltd.
Bibliographic Information
- Other Title
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- 新規殺虫剤ピリダリルの昆虫由来培養細胞Sf9に対する毒性
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Description
The effect of pyridalyl on cultured Sf9 cells was compared with that of various known cytotoxic and non-cytotoxic substances. Cell growth was significantly inhibited by the cytotoxic substances at 10 μM, but not significantly inhibited by the non-cytotoxic substances. Pyridalyl clearly inhibited the growth of cells at a concentration of 0.01 μM. Analogues of pyridalyl with insecticidal activity also inhibited cell growth, but those without insecticidal activity did not have significant effects. The test system was considered valid and the cytotoxicity of pyridalyl in Sf9 cells reflects its insecticidal action at least in part. Pyridalyl did not, however, affect mitochondrial respiration, which is the most likely cause of the cytotoxicity. © Pesticide Science Society of Japan
Journal
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- Journal of Pesticide Science
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Journal of Pesticide Science 30 (1), 17-21, 2005
Pesticide Science Society of Japan
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Details 詳細情報について
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- CRID
- 1390001205211038336
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- NII Article ID
- 110001711197
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- NII Book ID
- AA11818622
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- ISSN
- 13490923
- 03851559
- 1348589X
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- NDL BIB ID
- 7252257
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- Text Lang
- en
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- NDL-Digital
- CiNii Articles
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- Abstract License Flag
- Disallowed