Significance of postoperative chemoradiotherapy for advanced hypopharyngeal cancer

DOI 4 Citations 8 References
  • Tanaka Shinzo
    Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Graduate School of Medicine
  • Asato Ryo
    Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Graduate School of Medicine
  • Nagata Yasushi
    Department of Radiology, Kyoto University, Graduate School of Medicine
  • Hirano Shigeru
    Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Graduate School of Medicine
  • Tamura Yoshihiro
    Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Graduate School of Medicine
  • Honda Keigo
    Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Graduate School of Medicine
  • Ito Juichi
    Department of Otolaryngology-Head and Neck Surgery, Kyoto University, Graduate School of Medicine
  • Hiraoka Masahiro
    Department of Radiology, Kyoto University, Graduate School of Medicine

Bibliographic Information

Other Title
  • 下咽頭進行癌の術後治療と予後

Search this article

Abstract

Thirty-nine consecutive patients with advanced hypopharyngeal cancer (HPC) in Kyoto University Hospital from 2000 to 2005 were treated with extended surgery and postoperative radiotherapy in which a dose of 50 Gy was usually irradiated on the neck bilaterally and 10 Gy was added for patients who were thought to be at high risk of locoregional recurrence from the histopathological evaluation of surgical specimens, e.g. postpharyngeal lymph node metastasis, multiple metastases or insufficient safety margin. Chemotherapy was also combined in the high-risk patients. Disease-specific 3-year survival was 77%, and only three patients died from locoregional recurrence. Compared with the previous 25 patients of advanced HPC who were treated with the usual 50 Gy radiation postoperatively, the rate of recurrence in regional lymph nodes was clearly reduced. Postoperative chemoradiotherapy with increased intensity according to the risk of recurrence may be useful in locoregional control for advanced HPC.

Journal

  • Toukeibu Gan

    Toukeibu Gan 33 (1), 26-29, 2007

    Japan Society for Head and Neck Cancer

Citations (4)*help

See more

References(8)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top