基質拡張型β–ラクタマーゼ(extended-spectrum β–lactamase: ESBL)産生<i>Klebsiella oxytoca</i>のアウトブレイクの対応に関する検討
書誌事項
- タイトル別名
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- Investigation of the Outbreak of Extended Spectrum Beta-Lactamase-Producing Klebsiella oxytoca
- キシツ カクチョウガタv-ラクタマーゼ(extended-spectrum v-lactamase : ESBL)サンセイ Klebsiella oxytoca ノ アウトブレイク ノ タイオウ ニ カンスル ケントウ
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Since extended spectrum β-lactamase (ESBL) genes are located on a plasmid, transmission of ESBL genes might be possible beyond bacterial species. Therefore, resistant bacteria with ESBL genes might spread quickly and cause serious nosocomial infections. The outbreak of ESBL-producing Klebsiella oxytoca was detected in the neurosurgery ward of our hospital. Analysis using pulsed-field gel electrophoresis (PFGE) revealed horizontal transmission of only one strain. Since only reinforced hand hygiene was not effective to control the outbreak, we performed not only reinforced contact precautions but also education for medical staff and active screening for patients and medical staff, and isolation of patients. Such measures could lead to reduction of the outbreak. We considered that delay in aggressive intervention by the ICT would be associated with longer duration of the outbreak. We conclude that ICT intervention from the early stage and aggressive isolation strategy are necessary to control outbreaks of ESBL-producing bacteria.<br>
収録刊行物
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- 日本環境感染学会誌
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日本環境感染学会誌 27 (5), 315-322, 2012
一般社団法人 日本環境感染学会
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詳細情報 詳細情報について
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- CRID
- 1390001205297372032
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- NII論文ID
- 130002575254
- 40019445079
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- NII書誌ID
- AA12313188
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- ISSN
- 18832407
- 1882532X
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- NDL書誌ID
- 024006455
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
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- 抄録ライセンスフラグ
- 使用不可