α-トコフェロールのレベルならびに糖質の種類を異にした食餌を与えたラットの肝臓, 血漿の脂質成分

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書誌事項

タイトル別名
  • The Effects of the Dietary α-Tocopherol and Different Sugars on Liver and Plasma Lipids in Rats
  • アルファ トコフェロール ノ レベル ナラビニ トウシツ ノ シュルイ オ イ

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説明

The present study is focussed on examining the influences of dietary tocopherol on plasma and liver lipids in rats, in an appropriate combination with different dietary sugars (glucose, sucrose or fructose). Male and female rats of Wistar strain were fed diets ad libitum for 2 weeks. dl-α-Tocopheryl acetate was added to the diets in three different levels (A, B and C groups) depending on the conditions of the experiments.<BR>(1) The concentrations of plasma cholesterol and triglyceride were not necessarily reduced by increasing tocopherol levels in the diets. In some groups of rats fed fructose, the accumulation of liver triglyceride was essentially prevented by the administration of increasing levels of tocopherol.<BR>(2) Tocopherol supplementation caused, in most cases of the experiments using sucrose or fructose as dietary sugars, marked changes in percentage of hepatic arachidonic acid compared with those of other polyunsaturated fatty acids.<BR>(3) The alterations of plasma and liver lipids by dietary tocopherol were most remarkable in rats fed fructose.<BR>(4) From the results of these experiments, it is apparent that the effects of tocopherol on plasma and liver lipids differ with the sources of dietary sugars and other constituents and/or body weights and sexes of the experimental animals.

収録刊行物

  • 栄養と食糧

    栄養と食糧 30 (5), 275-281, 1977

    公益社団法人 日本栄養・食糧学会

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