実験的糖尿病白ネズミにおける膜消化酵素の日内変動

DOI Web Site

書誌事項

タイトル別名
  • The Diurnal Rhythms of Intestinal Digestive Enzymes in Diabetic Rats
  • ジッケンテキ トウニョウビョウ ハク ネズミ ニ オケル マク ショウカ コウ

この論文をさがす

説明

The diurnal rhythms of intestinal digestive enzymes were observed in streptozotocin-induced diabetic rats. Rats were raised under artificial light (light; 9: 00-21: 00, dark; 21: 00-9: 00) and fed during the dark. Water was given ad libitum.<BR>Diabetic rats showed high concentration of blood glucose and urinary glucose. The body weight gain of diabetic rats was less than that of normal rats. However, the wet weight of intestinal mucosa in diabetic rats was significantly increased as compared with normal rats, especially in the dark.<BR>A typical diurnal rhythm of sucrase activity, specific and total activity, which is low in the light and high in the dark, was observed in normal rats. On the other hand, in diabetic rats, the specific activity of sucrase increased in the light, and was similar or decreased in the dark compared with normal rat, especially in duodenum and jejunum. Therefore, the diurnal variation of specific activity of sucrase was smaller in diabetic rats than in normal rats. However, a typical diurnal rhythm was shown in total activity. Isomaltase activity showed similar pattern as sucrase activity.<BR>Alkaline phosphatase activity showed a diurnal rhythm in normal and diabetic rats.

収録刊行物

  • 栄養と食糧

    栄養と食糧 33 (3), 185-189, 1980

    公益社団法人 日本栄養・食糧学会

詳細情報 詳細情報について

問題の指摘

ページトップへ