書誌事項
- タイトル別名
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- Investigation of the risk factor for foot complications in subjects with diabetic nephropathy
- トウニョウビョウセイジンショウ カンジャ ニ オケル ジュウショウ ソク ビョウヘン ハッショウ キケン インシ ノ ケントウ
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抄録
Objective: Among diabetic patients, end-stage renal disease, in particular hemodialysis, relates to the occurrence of diabetic foot. We investigated the foot complications among diabetic nephropathies before hemodialysis. Methods: There were 106 patients [80 male, average age 62.0 (33–80) years, diabetic duration 17.7±8.8 years, HbA1c (NGSP) 7.7±1.5%, serum creatine 1.9±0.9 mg/dl, eGFR (estimated glomerular filtration rate) 33.0±14.5 ml/min/1.73m2]. We evaluated the occurrence of the foot complications and analyzed the risk factors by the Cox proportional hazards model. Results: The mean observation period was 32.4±22.2 months, and 10 patients underwent therapy for diabetic foot. By multivariate analysis, smoking, diastolic blood pressure and serum creatinine level were significantly associated with the event of diabetic foot [hazard ratio (HR): 13.0, 95% confidence interval (CI): 1.16–435.8, HR: 1.18, 95% CI: 1.03–1.37, HR: 9.03, 95% CI: 1.05–123.6]. Conclusions: It was suggested for the optimal prevention of diabetic foot complications, a multilateral approach was necessary, especially life-support instruction for smoking cessation and therapeutic intervention for hypertension and renal dysfunction.
収録刊行物
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- 日本下肢救済・足病学会誌
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日本下肢救済・足病学会誌 4 (3), 173-177, 2012
日本下肢救済・足病学会
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詳細情報 詳細情報について
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- CRID
- 1390001205337557376
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- NII論文ID
- 130001930764
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- NII書誌ID
- AA12678449
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- ISSN
- 21871957
- 1883857X
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- NDL書誌ID
- 024029109
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可