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- 右馬 文彦
- 関西医科大学第一内科学教室
書誌事項
- タイトル別名
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- Studies on the Effects of Antibiotics on Capillary Permeability
- 各種抗生物質の血管透過性におよぼす影響-1-各種抗生物質の血管内残留色素量におよぼす影響について
- カクシュ コウセイ ブッシツ ノ ケッカン トウカセイ ニ オヨボス エイキョ
- Part II. The Effects of Antibiotics on Dye Concen t rations in Blood Vessels
- 第1編各種抗生物質の血管内残留色素量におよぼす影響について
この論文をさがす
抄録
Using dyes to observe the influence on capillary permeability produced by antibiotics (CBPC, SBPC, CET, and CEZ administered i. v. at 400 & 9mg/kg) in rats, the changes in dye concentrations in the blood vessels were examined at 5,15,30, and 60 minutes following antibiotic administration in comparison with i. v. NaC1 administration. The results were as follows<BR>1) Using Ev a ns blue 25mg/kg: Evans blue was decreased after antibiotic (400mg/kg) i. v. administration at 5 to 30minutes, markedly so after 5 minutes.<BR>2) Using Evans blue 5mg/kg or Rhodamine B 5mg/kg: These dye concentrations were decreased by antibiotics (400mg/kg)at 5 to 30 minutes, clearly so after 5 minutes, and by antibiotics (9mg/kg) at 5 to 15 minutes, the effects of the latter dosage being weaker than these of the former.<BR>3) The Evans blue concentrations varied with the quantity of phys. NaC1 solution.<BR>4) Using Histamine i. m. and i. v.: Evans blue concentrations were de creased by Histamine i. m. and i. v. at 30 to 60minutes, markedly so after 60 minutes.<BR>5) Using Urokinase i. v.: Urokinase i. v. had no influ ence on dye concentration.
収録刊行物
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- The Journal of Kansai Medical University
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The Journal of Kansai Medical University 30 (2), 192-208, 1978
The Medical Society of Kansai Medical University
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詳細情報 詳細情報について
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- CRID
- 1390001205458299008
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- NII論文ID
- 130004625416
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- NII書誌ID
- AN00046712
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- COI
- 1:CAS:528:DyaE1MXkvVegsLc%3D
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- NDL書誌ID
- 2073120
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- ISSN
- 00228400
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可