書誌事項
- タイトル別名
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- Histopathological study on dibutyltin dichloride-induced bile duct dilatation in rats
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抄録
Male Lewis rats treated intravenously with a single dose of dibuthyltin dichloride (DBTC)showed epithelial damage in the extrahepatic bile duct, chronic inflammation, and sequential obstruction and cystic dilatation of the bile duct. In the liver, cholangiolitis and proliferation of bile ducts was characteristic, and the animals with marked inflammation showed cirrhosis-like structures. Taking these facts together, we consider these DBTC treated rats to be a model of bile duct dilatation or biliary cirrhosis found in humans.<BR>Bile duct dilatation in humans is thought to be related to an abnormal pancreatico-choledochal duct junction. Also in this model, one of the cause of pathologic condition may owe to the anastomosis of pancreatic duct and bile one. So we may have a clue to solving the mechanism whereby bile duct dilatation occurs in human.
収録刊行物
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- Tando
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Tando 16 (2), 94-99, 2002
Japan Biliary Association
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詳細情報 詳細情報について
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- CRID
- 1390001205465740416
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- NII論文ID
- 130004675665
- 10020605602
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- NII書誌ID
- AN10062001
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- ISSN
- 09140077
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可