急性化膿性中耳炎ならびに急性扁桃炎に対するAmikacin (BB-K8) の薬効評価
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- 馬場 駿吉
- Department of Otorhinolaryngology, Nagoya City University School of Medicine
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- 三辺 武右衛門
- Department of Otorhinolaryngology, Kanto Teishin Hospital
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- 村上 温子
- Department of Otorhinolaryngology, Kanto Teishin Hospital
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- 上田 良穂
- Department of Otorhinolaryngology, Kanto Teishin Hospital
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- 佐藤 喜一
- Department of Pathology, Medical Research Institute, Tokyo Medical and Dental University
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- 粟田口 省吾
- Department of Otorhinolaryngology, Hirosaki University School of Medicine
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- 平岡 真理子
- Department of Otorhinolaryngology, Hirosaki University School of Medicine
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- 鎌田 重輝
- Department of Otorhinolaryngology, Hirosaki University School of Medicine
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- 川畑 武裕
- Department of Otorhinolaryngology, Hirosaki University School of Medicine
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- 河村 正三
- Department of Otorhinolaryngology, Juntendo University School of Medicine
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- 市川 銀一郎
- Department of Otorhinolaryngology, Juntendo University School of Medicine
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- 杉田 麟也
- Department of Otorhinolaryngology, Juntendo University School of Medicine
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- 法水 正文
- Department of Otorhinolaryngology, Tokyo Teishin Hospital, Tokyo, Japan
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- 大沢 博之
- Department of Otorhinolaryngology, Tokyo Teishin Hospital, Tokyo, Japan
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- 斎藤 洋三
- Department of Otorhinolaryngology, Tokyo Medical and Dental University
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- 小川 明
- Department of Otorhinolaryngology, Tokyo Medical and Dental University
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- 渋井 弘一
- Department of Otorhinolaryngology, Asoka Hospital
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- 南条 昭一
- Department of Otorhinolaryngology, Kanto Chuo Hospital
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- 高藤 次夫
- Department of Otorhinolaryngology, Tokyo Kosei Nenkin Hospital
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- 中野 達衣
- Department of Otorhinolaryngology, Tokyo Kosei Nenkin Hospital
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- 小倉 脩二
- Department of Otorhinolaryngology, Japan Red Cross Medical Center
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- 益子 三郎
- Department of Otorhinolaryngology, Japan Red Cross Medical Center
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- 高須 照男
- Department of Otorhinolaryngology, Fujitagakuen University School of Medicine
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- 岩田 重信
- Department of Otorhinolaryngology, Fujitagakuen University School of Medicine
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- 関谷 忠雄
- Department of Otorhinolaryngology, Nagoya National Hospital, Nagoya, Japan
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- 大塚 基
- Department of Otorhinolaryngology, Nagoya National Hospital, Nagoya, Japan
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- 山本 馨
- Department of Otorhinolaryngology, Osaka City University School of Medicine
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- 杉山 正夫
- Department of Otorhinolaryngology, Osaka City University School of Medicine
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- 山本 正宏
- Department of Otorhinolaryngology, Osaka City University School of Medicine
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- 武田 一雄
- Department of Otorhinolaryngology, Osaka Medical College
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- 中村 文昭
- Department of Otorhinolaryngology, Osaka Medical College
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- 石井 宏典
- Department of Otorhinolaryngology, Osaka Medical College
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- 広戸 幾一郎
- Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University
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- 渡辺 晋
- Department of Otorhinolaryngology, Kyushu Kosei Nenkin Hospital
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- 村田 義治
- Department of Otorhinolaryngology, Kyushu Kosei Nenkin Hospital
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- 佐久間 昭
- Department of Clinical Pharmacology, Medical Research Institute, Tokyo Medical and Dental University
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- 小酒井 望
- Department of Clinical Pathology, Juntendo University School of Medicine
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- 小栗 豊子
- Department of Clinical Pathology, Juntendo University School of Medicine
書誌事項
- タイトル別名
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- Double-Blind Trial of Amikacin (BB-K8)in the Treatment of Acute Supprative Otitis Media and Acute Tonsillitis
- -Aminodeoxykanamycinとの二重盲検試験による検討-
この論文をさがす
抄録
To evaluate objectively the effect of amikacin (BB-K8) on acute supprative otitis media and acute tonsillitis, a double-blind trial was carried out using aminodeoxykanamycin (AKM) as a control drug.<BR>Effectiveness rate by total judgement on each disease in adult and primary school patients was 54.6% in BB-K8 and 70.0% in AKM in adult patients with acute supprative otitis media, and 83.3% in BB-K8 and 61.7% in AKM in primary school patients with supprative otitis media. Also it was 76.6% in BB-K8 and 75.5% in AKM in adult patients with acute tonsillitis, and 94.1% in BB-K8 and 88.2% in AKM in primary school patients with acute tonsillitis.<BR>Statistical superiority of BB-K8 to AKM was noted in primary school patients with acute supprative otitis media (P<0.1).<BR>In adult patients with acute supprative otitis media relatively higher effectiveness rate was seemingly obtained in AKM in comparison with BB-K8. Such results as obtained above and the assessments made in AKM so far may be concluded efficacy of BB-K8. As to the adverse reactions there observed no difference between both agents and no abnormality in hearing acuity was noted.
収録刊行物
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- 耳鼻と臨床
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耳鼻と臨床 22 (1), 51-76, 1976
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詳細情報 詳細情報について
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- CRID
- 1390001205496338432
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- NII論文ID
- 130004132733
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- ISSN
- 04477227
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可