EFFECT OF 1-(2-CHLOROETHYL)-3-(β-D-GLUCOPYRANOSYL)-1-NITROSOUREA ON EXPERIMENTAL TUMORS
書誌事項
- タイトル別名
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- Effect of 1 2 Chloroethyl 3 ベータ D gluco
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抄録
A newly synthesized water-soluble nitrosourea derivative, 1-(2-chloroethyl)-3-(β-D-glucopyranosyl)-1-nitrosourea (GANU; NSC-254157) has marked activities against experimental tumors such as lymphoid leukemia L-1210, ascites sarcoma-180, ascites hepatoma AH-130, and Walker carcinosarcoma-256. A single intraperitoneal injection of the compound is more effective than successive injections on the L-1210 system.<br>An especially interesting point is that both the single intraperitoneal and single oral administrations 2 days after tumor implantation showed a high effectiveness. In addition, growth of the mammary adenocarcinoma transplanted subcutaneously on the back of mice was also considerably suppressed by successive intraperitoneal injections of the compound.
収録刊行物
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- GANN Japanese Journal of Cancer Research
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GANN Japanese Journal of Cancer Research 68 (6), 819-824, 1977
日本癌学会
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詳細情報 詳細情報について
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- CRID
- 1390001205529324160
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- NII論文ID
- 40000528970
- 130006409779
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- NII書誌ID
- AN00045888
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- NDL書誌ID
- 1917540
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- ISSN
- 0016450X
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可