EFFECT OF N-(3, 5-DICHLOROPHENYL)SUCCINIMIDE ON THE HISTOLOGICAL PATTERN AND INCIDENCE OF KIDNEY TUMORS INDUCED BY STREPTOZOTOCIN IN RATS
書誌事項
- タイトル別名
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- Effect of N 3 5 Dichlorophenyl succinim
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抄録
The effect of the nephrotoxic substance, N-(3, 5-dichlorophenyl) succinimide, on the histological pattern and incidence of kidney tumors induced by streptozotocin in rats was studied. In groups administered streptozotocin alone or in combination with nicotinamide, the histological pattern and the incidence of kidney tumors in rats were similar; renal cell tumors developed in 1 of 9 rats (11.1%) and in 2 of 17 rats (11.8%), respectively. However, post-treatment with N-(3, 5-dichlorophenyl) succinimide increased the induction of epithelial tumors by streptozotocin, and embryonal cell tumors were also induced nearly as frequently. Administration of nicotinamide alone did not result in the development of kidney tumors.
収録刊行物
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- GANN Japanese Journal of Cancer Research
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GANN Japanese Journal of Cancer Research 68 (4), 397-404, 1977
日本癌学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390001205529842176
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- NII論文ID
- 130006409635
- 40000528999
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- NII書誌ID
- AN00045888
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- NDL書誌ID
- 1838431
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- ISSN
- 0016450X
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可