表皮ミトコンドリアのビタミンB_6依存性脂肪酸合成酵素について

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書誌事項

タイトル別名
  • Separation and Identification of the B_6-Dependent Fatty Acid Synthetase from Epidermal Mitochondria
  • ヒョウヒ ミトコンドリア ノ ビタミン B6 イゾンセイ シボウサン ゴウセイ コウソ ニ ツイテ

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抄録

The incorporation of acetyl CoA into fatty acid by epidermal mitochondria was confirmed. Elongation of short chain fatty acids with one C_2 unit-acetyl-CoA was a major reaction. The dialyzate of the freezed and thawed epidermal mitochondria lost its activity, which was recovered completly by adding 0.4μm of pyridoxal phosphate. The enzymic activity was purified to 133 fold the potency after DEAE-cellulose column treatment. ATP, NADPH and NADH were required as cofactors.

収録刊行物

  • ビタミン

    ビタミン 42 (5), 280-287, 1970

    公益社団法人 日本ビタミン学会

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