3,4´-O-Isopropylidene Pyridoxineと4´,5´-O-Isopropylidene Pyridoxineのラットにおける代謝

DOI Web Site

書誌事項

タイトル別名
  • Metabolism of 3,4´-O-Isopropylidene Pyridoxine and 4´,5-O-Isopropylidene Pyridoxine in Rats
  • 3,4′-O-Isopropylidene Pyridoxineと4′,5′-O-Isopropylidene Pyridoxineのラットにおける代謝
  • 3 4 O Isopropylidene Pyridoxine ト 4 5 O

この論文をさがす

説明

Metabolism of 3,4'-O-isopropylidene pyridoxine (3,4'-IPP) and 4',5'-O-isopropylidene pyridoxine (4',5'-IPP) was studied in rats. Following an oral or intraperitoneal administration of 3,4'-IPP, urinary excretion of pyridoxine (PN) was about 2~5% of the administered dose at mole base. About 20% of orally administered 4',5'-IPP were excreted as PN in the urine, but about 1~2% were detected as PN in the urine after an intraperitoneal injection. A metabolite of 4',5'-IPP in the urine was separated and purified by chromatographic techniques. The metabolite was assumed to be 4',5'-IPP 3-sulfate by measurement of Rf values on thin-layer chromatography and ultraviolet absorption spectra, identification of acid hydrolyzed product and detection of sulfate ion after acid hydrolysis.

収録刊行物

  • ビタミン

    ビタミン 54 (3), 89-93, 1980

    公益社団法人 日本ビタミン学会

詳細情報 詳細情報について

問題の指摘

ページトップへ