書誌事項
- タイトル別名
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- Entry Mechanism of Morbillivirus Family
- モルビリウイルスゾク ノ サイボウ シンニュウ キコウ
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抄録
The genus Morbillivirus includes measles virus, canine distemper virus and rinderpest virus. These are highly contagious and exhibit high mortality. These viruses have the attachment glycoprotein, hemagglutinin (H), at the virus surface, which bind to signaling lymphocyte activation molecule (SLAM) and Nectin 4 as receptors for the entry. However, the molecular mechanism for this entry has been limitedly understood. Here we summarize the current topics, (1) newly identified receptor, Nectin 4, (2) crystal structures of H-receptor complexes and (3) detail biochemical studies of the H-F communication for the entry. These provide insight on the mechanism of morbillivirus entry event and furthermore drug developments.<br>
収録刊行物
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- 薬学雑誌
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薬学雑誌 133 (5), 549-559, 2013-05-01
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001206129120512
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- NII論文ID
- 130003361948
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- NII書誌ID
- AN00284903
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- COI
- 1:STN:280:DC%2BC3snhsVKnsg%3D%3D
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- ISSN
- 13475231
- 00316903
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- NDL書誌ID
- 024650747
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- PubMed
- 23649396
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可