Response of Type B and E Botulinum Toxins to Purified Sulfhydryl-Dependent Protease Produced by Clostridum Botulinum Type F
書誌事項
- タイトル別名
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- RESPONSE OF TYPE B AND E BOTULINUM TOXINS TO PURIFIED SULFHYDRYL-DEPENDENT PROTEASE PRODUCED BY<I> CLOSTRIDIUM BOTULINUM</I> TYPE F
- Response of Type B and E Botulinum Toxi
- RESPONSE OF TYPE B AND E BOTULINUM TOXINS TO PURIFIED SULFHYDRYL-DEPENDENT PROTEASE PRODUCED BY CLOSTRIDIUM BOTULINUM TYPE F
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説明
A sulfhydryl-dependent protease (SHP) was purified from a culture ofClostridium botulinumtype F. The enzyme can activate type E progenitor toxin completely but type B progenitor toxin only partially. This may suggest that SHP by itself could completely activate the toxin of proteolyticC. botulinumtypes A and F in culture. The toxicity of type E progenitor toxin potentiated by the treatment with SHP persisted, whereas that of derivative toxin decreased rapidly by further incubation with SHP. This may indicate that only the progenitor toxin, the complex of the toxic and nontoxic components, activated by SHP withstands the subsequent exposure to the enzyme in cultures of proteolyticC. botulinum.
収録刊行物
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- Ｊａｐａｎｅｓｅ Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ ａｎｄ Ｂｉｏｌｏｇｙ
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Ｊａｐａｎｅｓｅ Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ ａｎｄ Ｂｉｏｌｏｇｙ 30 (4), 179-190, 1977
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
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詳細情報 詳細情報について
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- CRID
- 1390001206242152320
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- NII論文ID
- 130003953256
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- NII書誌ID
- AA1132885X
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- COI
- 1:CAS:528:DyaE2sXlvFKht7s%3D
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- ISSN
- 18842828
- 00215112
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- NDL書誌ID
- 1837838
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- PubMed
- 20527
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
