小児副鼻腔炎由来肺炎球菌の薬剤感受性パターン

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  • The drug susceptibility pattern of Streptococcus pneumoniae from pediatric sinusitis.

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We investigated the drug susceptibility pattern of Streptococcus pneumoniae and viridans streptococci from pediatric sinusitis that were obtained from October 1995 to June 1996. The results are summarized as follows;<BR>1. The frequency of detection of penicillin (PC)-intermediate S. pneumoniae (PISP)+PC-resistant S. pneumoniae (PRSP) was 49.6% in the 188 strains obtained, and that of PISP was high. The MIC distribution of drug susceptibility of cefditoren for PISP+PRSP was the lowest.<BR>2. The serovariants or serogroups of PSSP were widely distributed many serovariants, but those of PISP+PRSP were almost 19, 23 and 6 type.<BR>3. The frequency of detection of macrolides (MLs)-resistance of both PSSP and PISP+PRSP was high. And that of MLs-constitutive-resistant strains of PSSP and that of MLs-induced resistant strains of PISP+PRSP were high.<BR>4. The frequency of detection of multiple drug-resistant strains of Streptococcus oralis and Streptococcus mitis was high. The drug susceptibility patterns of those organisms were similar to that of S. pneumoniae.

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