INFLUENCES OF VARIOUS CHEMICAL REAGENTS ON THE BIOLOGICAL ACTIVITIES OF S-PAROTIN
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- AONUMA SHIGERU
- Pharmaceutical Faculty, University of Osaka
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- HAMA TAKAO
- Pharmaceutical Faculty, University of Osaka
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- HONDA HIROKO
- Pharmaceutical Faculty, University of Osaka
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- ITO YOSOJI
- Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, University of Tokyo
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- SHINODA MASATO
- Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, University of Tokyo
書誌事項
- タイトル別名
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- STUDIES ON SUBMAXILLARY GLAND XII
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説明
The activities of S-Parotin in aqueous solution were relatively stable against acid and alkaline. In solid state, S-Parotin could be stored for 4 years at room temperature without any remarkable loss of the activity. The activities reversiblly denaturated by urea. Ca-decreasing activity received non-reversible denaturation by guanidine hydrochloride, but Leucocytes decreasing and then increasing activity did not receive any denaturation. From the results of S-Parotin treated with nitrous acid, formaldehyde, iodine, cysteine and thioglycollic acid, it could concluded that there is no particularly responsible radical for the display of activities and the free amino radical and the tyrosine phenyl radical are responsible.
収録刊行物
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- Ｅｎｄｏｃｒｉｎｏｌｏｇｉａ Ｊａｐｏｎｉｃａ
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Ｅｎｄｏｃｒｉｎｏｌｏｇｉａ Ｊａｐｏｎｉｃａ 5 (4), 256-264, 1958
一般社団法人 日本内分泌学会
