高頻度の姉妹染色分体交換（Ｓｉｓｔｅｒ　ｃｈｒｏｍａｔｏｉｄ　ｅｘｃｈａｎｇｅ）とけいれん斑発作を合併したＳｃｈｏｅｎｌｅｉｎ－Ｈｅｎｏｃｈ紫斑病の１例

DOI

書誌事項

タイトル別名
  • A case of the Schoenlein-Henoch purpura with generalized seizures and high frequency of sister chromatoid exchanges.

抄録

A 13-year-old boy of the Schönlein-Henoch purpura with generalized seizures and high frequency of sister chromatoid exchanges is reported.<br>He suffered from abdominal pain and nausea in July 1986 and after a few days developed blepharoedema, facial exanthema, hematuria, bloody stool and generalized seizures.<br>He was admitted to our hospital on September 18, 1986. His family history was negative. Urinalysis revealed hematuria and proteinuria. EEG showed diffuse paroxysmal slow waves. Needle biopsy of a kidney revealed mesenchymal proliferation and deposits of IgA, IgM and fibrinogen. Chromosome analysis showed high frequency of sister chromatoid exchanges. His parent had high frequency, too.<br>It is not known why generalized seizures occur in the Schönlein-Henoch purpura.<br>This may be the first case report of the Schönlein-Henoch purpura that showed high frequency of sister chromatoid exchanges.<br>This suggest that etiology of generalized seizures may be associated with genetic factors.

収録刊行物

  • 医療

    医療 43 (11), 1211-1213, 1989

    一般社団法人 国立医療学会

キーワード

詳細情報 詳細情報について

  • CRID
    1390001206312858240
  • NII論文ID
    130004107165
  • DOI
    10.11261/iryo1946.43.1211
  • ISSN
    18848729
    00211699
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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