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- IZAIKE Yoshiaki
- National Institute of Animal Industry Livestock Div., Chugoku Agri. Exp. St.
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- SUGA Tetsuyuki
- National Institute of Animal Industry Faculty of Agriculture, Yamaguchi University
Bibliographic Information
- Other Title
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- 子宮内膜のDNA合成に及ぼす卵巣ホルモンの影響 卵巣摘出ラット子宮内膜におけるエストロゲン投与とDNA合成能の関係
- シキュウ ナイマク ノ DNA ゴウセイ ニ オヨボス ランソウ ホルモン ノ
- 卵巣摘出ラット子宮内膜におけるestrogen投与とDNA合成能の関係
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Abstract
Autoradiographic study using 3H-6-thymidine was carried out to investigate the effect of estrogen on the induction of DNA synthesis in uterine endometorium of ovaryectomized rats. Wistar strain rats weighing about 200 g were ovaryectomized, and 16 days later, a single dose of estradio1-17β was intramuscularly administered.<BR>1) 3H-6-thymidine uptake by the endometorium after a single injection of 10 μg estradiol-17β was determined by in vivo and in vitro methods, and there was no difference between the two.<BR>2) DNA synthesis was specifically increased in the surface epithelium after administration of estradiol-17β but no significant increase was observed both in stroma and glandular epithelium.<BR>3) Change of the 3H-6-thymidine up take after a single injection of estradio1-17 β was examined, the maximum up take was detected 24 h after the injection.<BR>4) A dose of 10 μg estradio1-17 β could induced the maximum up take of the labelled thymidine by the surface epithelium.
Journal
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- The Japanese journal of animal reproduction
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The Japanese journal of animal reproduction 26 (4), 174-177, 1980
THE SOCIETY FOR REPRODUCTION AND DEVELOPMENT
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Details 詳細情報について
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- CRID
- 1390001206333612800
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- NII Article ID
- 130004213941
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- NII Book ID
- AN00041843
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- NDL BIB ID
- 2297412
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- ISSN
- 03859932
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed