書誌事項
- タイトル別名
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- Effect of ovarian hormones on DNA synthesis in uteline endometorium
- シキュウ ナイマク ノ DNA ゴウセイ ニ オヨボス ランソウ ホルモン ノ
- 卵巣摘出ラット子宮内膜におけるestrogen投与とDNA合成能の関係
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抄録
Autoradiographic study using 3H-6-thymidine was carried out to investigate the effect of estrogen on the induction of DNA synthesis in uterine endometorium of ovaryectomized rats. Wistar strain rats weighing about 200 g were ovaryectomized, and 16 days later, a single dose of estradio1-17β was intramuscularly administered.<BR>1) 3H-6-thymidine uptake by the endometorium after a single injection of 10 μg estradiol-17β was determined by in vivo and in vitro methods, and there was no difference between the two.<BR>2) DNA synthesis was specifically increased in the surface epithelium after administration of estradiol-17β but no significant increase was observed both in stroma and glandular epithelium.<BR>3) Change of the 3H-6-thymidine up take after a single injection of estradio1-17 β was examined, the maximum up take was detected 24 h after the injection.<BR>4) A dose of 10 μg estradio1-17 β could induced the maximum up take of the labelled thymidine by the surface epithelium.
収録刊行物
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- 家畜繁殖学雑誌
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家畜繁殖学雑誌 26 (4), 174-177, 1980
日本繁殖生物学会
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詳細情報 詳細情報について
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- CRID
- 1390001206333612800
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- NII論文ID
- 130004213941
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- NII書誌ID
- AN00041843
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- NDL書誌ID
- 2297412
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- ISSN
- 03859932
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可