早期アルツハイマー型痴呆診断支援システム（ＶＳＲＡＤ）における水平断画像の有用性

DOI Web Site PubMed 被引用文献3件 参考文献11件

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タイトル別名
  • Utility of Axial Images in an Early Alzheimer Disease Diagnosis Support System (VSRAD)
  • 早期アルツハイマー型痴呆診断支援システム(VSRAD)における水平断面像の有用性
  • ソウキ アルツハイマーガタ チホウ シンダン シエン システム VSRAD ニ オケル スイヘイ ダンメンゾウ ノ ユウヨウセイ

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In recent years, voxel-based morphometry (VBM) has become a popular tool for the early diagnosis of Alzheimer disease. The Voxel-Based Specific Regional Analysis System for Alzheimer's Disease (VSRAD), a VBM system that uses MRI, has been reported to be clinically useful. The able-bodied person database (DB) of VSRAD, which employs sagittal plane imaging, is not suitable for analysis by axial plane imaging. However, axial plane imaging is useful for avoiding motion artifacts from the eyeball. Therefore, we created an able-bodied person DB by axial plane imaging and examined its utility. We also analyzed groups of able-bodied persons and persons with dementia by axial plane imaging and reviewed the validity. After using the DB of axial plane imaging, the Z-score of the intrahippocampal region improved by 8 in 13 instances. In all brains, the Z-score improved by 13 in all instances.

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