Inhibitory Effect of Non-Dialyzable Extract of Spinach on the Induction of Chromosomal Aberrations in CHL Cells by Carcinogens.

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  • KOBORI Masuko
    National Food Research Institute, The Ministry of Agriculture, Forestry and Fisheries
  • SAKUMA Isao
    Japan Food Research Laboratories
  • SHINOHARA Kazuki
    National Food Research Institute, The Ministry of Agriculture, Forestry and Fisheries

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  • 発がん物質で誘発されるCHL細胞の染色体異常に対するホウレンソウ非透析性抽出物の抑制効果
  • 発がん物質で誘発されるCHL細胞の染色体異常に対するホウレンソウ非透析性抽出物の抑制効果〔英文〕
  • ハツガン ブッシツ デ ユウハツサレル CHL サイボウ ノ センショクタイ

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Abstract

The effect of the non-dialyzable extract of fresh spinach leaves on the induction of chromosomal aberrations by some carcinogens was examined in a cultured Chinese hamster lung cell line (CHL). The non-dialyzable fraction was found to suppress the induction of chromosomal aberrations such as chromatid exchanges and chromatid breaks by N-methyl-N'-nitro-N-nitrosoguanidine, hydrogen peroxide and mitomycin C.

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