書誌事項
- タイトル別名
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- Immunologic properties of variants dissociated from serotype 1 Haemophilus paragallinarum strains.
- Haemophilus paragallinarum血清型1(血清型HA-1)菌株から作出した変異株の免疫学的性状〔英文〕
- Haemophilus paragallinarumケツセイガタ 1 ケツセイ
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抄録
Immunogenic properties of seven variants having different morphologic, serologic, and pathogenic properties, which were dissociated from serotype 1 (serotype HA-1) Haemophilus paragallinarum, were investigated in chicks. Protective immunity was induced by injection with any of the four variants possessed both heat-labile, trypsin-sensitive, hyaluronidase-resistant, serotype 1-specific L1 and HA-L1 antigens. The immuned chicks had antibodies specific to serotype 1, agglutinin against L1 antigen and hemagglutination-inhibition (HI) antibodies against HA-L1 antigen. In contrast, the other three variants lacking both the antigens did not induce protection. Hyaluronidase-treatment of the hi variant consisting of highly encapsulated organisms abolished its virulence without affecting the protective activity and antibody-producing ability against antigens L1 and HA-L1. These results support our hypothesis that the antigens L1 and HA-L1, are responsible for immunogenicity.
収録刊行物
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- 日本獸醫學雜誌(The Japanese Journal of Veterinary Science)
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日本獸醫學雜誌(The Japanese Journal of Veterinary Science) 46 (1), 49-56, 1984
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206422946176
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- NII論文ID
- 110003917193
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- NII書誌ID
- AN00191788
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- COI
- 1:STN:280:DyaL2c3ktlKrtQ%3D%3D
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- ISSN
- 18811442
- 00215295
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- NDL書誌ID
- 2988208
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- PubMed
- 6737827
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可