Termitomycesphins G and H, Additional Cerebrosides from the Edible Chinese Mushroom Termitomyces albuminosus
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- QU Yuan
- College of Pharmaceutical Sciences, Zhejiang University College of Pharmaceutical Sciences, Zhejiang University
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- SUN Kaiyue
- College of Pharmaceutical Sciences, Zhejiang University College of Pharmaceutical Sciences, Zhejiang University
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- GAO Lijuan
- College of Pharmaceutical Sciences, Zhejiang University College of Pharmaceutical Sciences, Zhejiang University
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- SAKAGAMI Youji
- Graduate School of Bioagricultural Sciences, Nagoya University Graduate School of Bioagricultural Sciences, Nagoya University
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- KAWAGISHI Hirokazu
- Graduate School of Science and Technology, Shizuoka University Graduate School of Science and Technology, Shizuoka University
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- OJIKA Makoto
- Graduate School of Bioagricultural Sciences, Nagoya University Graduate School of Bioagricultural Sciences, Nagoya University
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- QI Jianhua
- College of Pharmaceutical Sciences, Zhejiang University College of Pharmaceutical Sciences, Zhejiang University
書誌事項
- タイトル別名
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- Termitomycesphins G and H, Additional Cerebrosides from the Edible Chinese Mushroom <I>Termitomyces albuminosus</I>
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抄録
Two new cerebrosides, termitomycesphins G and H, were isolated from the edible Chinese mushroom, Termitomyces albuminosus (Berk.) Herm., and exhibited neuritogenic activity against PC12 cells. Their structures and absolute stereochemistry were elucidated by spectroscopic methods and by a comparison of the specific rotation of the hydrogenated products from termitomycesphins H and C. These cerebrosides possessed a unique modification by a hydroxyl group at the middle of the long-chain base, like earlier congeners termitomycesphins A–F. Termitomycesphin G with a 16-carbon-chain fatty acid showed higher neuritogenic activity than that of termitomycesphin H with an 18-carbon-chain fatty acid. This effect was observed within the termitomycesphins, suggesting that the chain length of the fatty acyl moiety played a key role in the neuritogenic activity.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 76 (4), 791-793, 2012
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390001206478543360
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- NII論文ID
- 10030751968
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- NII書誌ID
- AA10824164
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- COI
- 1:STN:280:DC%2BC38rjt1WhtA%3D%3D
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 023593173
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- PubMed
- 22484955
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可