高分子材料表面に形成されたフィブリンに対する細胞接着

書誌事項

タイトル別名
  • Cellular response to fibrin formed on polymer surface.
  • コウブンシ ザイリョウ ヒョウメン ニ ケイセイサレタ フィブリン ニ タイス

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抄録

In order to clarify how structures of fibrin are related to cellular attachment and how polymer materials affect cellular responses and fibrin structures, the responses of fibroblast (adhesion, growth and morphological changes) to fibrin fiber gel coated on sulfonated-polystyrene with varied negative charges were examined. It was found that negative charges on sulfonated-polystyrene surface affected fibrinogen-fibrin conversion, changed structures of fibrin gel formed on sulfonated-polystyrene and furthermore changed cellular responses. The results offer us fundamental informations about biomaterial design of artificial skin and artificial vessel.

収録刊行物

  • 高分子論文集

    高分子論文集 42 (11), 739-745, 1985

    公益社団法人 高分子学会

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