書誌事項
- タイトル別名
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- A case of drug-induced interstitial pneumonia possibly caused by S-1 treatment as postoperative adjuvant chemotherapy
- ジュツゴ ホジョ カガク リョウホウ ニ シヨウ シタ S-1 ガ ゲンイン ト オモワレル ヤクザイセイ カンシツセイ ハイエン ノ 1レイ
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抄録
S-1 chemotherapy is widely used to treat head and neck cancer. Reports of interstitial pneumonia as a side effect of S-1 chemotherapy are very rare.<br>We report a case of interstitial pneumonia possibly caused by S-1 treatment as postoperative adjuvant chemotherapy.<br>We gave S-1 as postoperative adjuvant chemotherapy for mandibular gingival carcinoma in a 80-year-old woman. She had a fever 53 days after starting S-1 chemotherapy. The X-ray films and computed tomography (CT) showed reticular shadows in both lung fields, and the patient was given a diagnosis of interstitial pneumonia. The results of a drug-induced lymphocyte stimulation test were positive against S-1. The total dose of S-1 until the onset of symptoms was 3360 mg. We immediately started steroid therapy and withdrew S-1 chemotherapy, and then the symptoms remarkably improved, as did the abnormal findings on CT.<br>In conclusion, when a patient has a high fever and dyspnea during S-1 therapy, drug-induced interstitial pneumonia should be included in the differential diagnosis.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 60 (6), 342-347, 2014
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001206531170816
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- NII論文ID
- 130005083473
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 025625088
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可