レナリドミド・デキサメタゾン療法で改善したPOEMS症候群による肺高血圧症

DOI Web Site PubMed

書誌事項

タイトル別名
  • Successful treatment of POEMS syndrome-associated pulmonary hypertension with lenalidomide and dexamethasone therapy
  • レナリドミド ・ デキサメタゾン リョウホウ デ カイゼン シタ POEMS ショウコウグン ニ ヨル ハイ コウケツアツショウ

この論文をさがす

抄録

<p>POEMS syndrome is often complicated by pulmonary hypertension. The standard therapy for patients with POEMS syndrome is high-dose chemotherapy followed by autologous stem cell transplantation. However, the safety of high-dose chemotherapy for patients complicated with pulmonary hypertension remains unclear, and the optimal therapy for these patients is yet to be establishment. Herein, we report the case of a 54-year-old woman with POEMS syndrome accompanied by pulmonary hypertension. We successfully and safely performed lenalidomide and dexamethasone (Ld) therapy followed by high-dose chemotherapy and autologous stem cell transplantation, which improved her pulmonary hypertension. Thus, Ld can be considered as safe and effective for pulmonary hypertension with POEMS syndrome.</p>

収録刊行物

  • 臨床血液

    臨床血液 59 (5), 489-491, 2018

    一般社団法人 日本血液学会

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ