ビタミンCが一過性の受動喫煙時の動脈機能に及ぼす影響

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タイトル別名
  • Effect of vitamin C ingestion on the vascular endothelial function exposed to transient passive smoking
  • ビタミン C ガ イッカセイ ノ ジュドウ キツエンジ ノ ドウミャク キノウ ニ オヨボス エイキョウ

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<p></p><p>As well as active smoking, passive smoking is associated with a high risk of developing cardiovascular disease. The antioxidant vitamin C may inhibit the unfavorable effects of passive smoking. In this study, we investigated the effects of vitamin C ingestion on changes in the flow-mediated dilatation (FMD) at the brachial artery in patients exposed to transient passive smoking. The study participants included seven healthy adult males who were examined by high-resolution ultrasonography of the brachial artery before and after 15-minute of passive smoking. FMD was used to examine the endothelial function. Randomized crossover controlled trial, measurements were performed on two different days 120-minute after the oral administration of 1000mg of ascorbic acid (VC trial) or a placebo (P trial). Although the FMD values decreased after passive smoking in both trials, the FMD values of the VC trial were higher than those of the P trial, with significant differences between the trials observed immediately and 30-minute after passive smoking. The results of this study suggested that the ingestion of vitamin C may suppress the decrease in the vascular endothelial function caused by transient passive smoking.</p>

収録刊行物

  • 体力科学

    体力科学 68 (2), 153-157, 2019-04-01

    一般社団法人日本体力医学会

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