東アジアにおけるヒトの遺伝適応の痕跡を求めて

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書誌事項

タイトル別名
  • SEARCH FOR SIGNATURES OF HUMAN GENETIC ADAPTATIONS IN EAST ASIA
  • ヒガシアジア ニ オケル ヒト ノ イデン テキオウ ノ コンセキ オ モトメテ

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抄録

Modern humans dispersed into East Asia approximately 40K years ago and genetically adapted to unprecedented environmental conditions. Signatures of local genetic adaptations, which are engraved in our genome, can be detected using population genomics approaches. Human genome variation data have enabled a comprehensive search for genetic variants showing such signatures as well as for those associated with phenotypic variation. Although our knowledge about local genetic adaptations has increased due to recent research efforts, little is known about what selective pressures acted on the selected variants.

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