書誌事項
- タイトル別名
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- Characterization and differentiation of positional isomers of fluoro-fentanyl analogs by a combination of instrumental analyses
- カクシュ キキ ブンセキ ニ ヨル フルオロ-フェンタニルルイ ノ イチ イセイタイ シキベツ
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説明
<p> The isomers of fluoro-butyrylfentanyl, fluoro-isobutyrylfentanyl, and fluoro-methoxyacetylfentanyl, in which the position of fluorine on the N-phenyl ring varies, were synthesized, characterized, and differentiated by infrared (IR) spectroscopy, liquid chromatography/mass spectrometry (LC/MS), and gas chromatography/mass spectrometry (GC/MS). The isomers could be clearly differentiated by their IR spectra. In the LC/MS chromatograms, the separation of the fluoro-butyrylfentanyl and fluoro-isobutyrylfentanyl isomers was insufficient. However, in the GC/MS extracted ion chromatograms, all compounds were completely separated. The LC/MS and GC/MS mass spectra of the isomers were similar, demonstrating that it is difficult to distinguish the positional isomers of fluorinated fentanyl analogs by their mass spectra.</p>
収録刊行物
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- 日本法科学技術学会誌
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日本法科学技術学会誌 24 (2), 123-133, 2019
日本法科学技術学会
