IMMUNOHISTOCHEMICAL INVESTIGATION OF OTOLARYNGOLOGICAL TISSUES LIKE TONSILS USING THE ANTIBODY WHICH SPECIFICALLY RECOGNIZES D-β-Asp.

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  • Takahashi Y.
    Department of Otolaryngology – Head and Neck Surgery, Yamagata University Faculty of Medicine
  • Ohta N.
    Department of Otolaryngology – Head and Neck Surgery, Yamagata University Faculty of Medicine
  • Suzuki Y.
    Department of Otolaryngology – Head and Neck Surgery, Yamagata University Faculty of Medicine
  • Kakehata S.
    Department of Otolaryngology – Head and Neck Surgery, Yamagata University Faculty of Medicine
  • Fujii N.
    Graduate School of Science, Kyoto University Division of Radiation Life Science, Kyoto University, Research Reactor Institute

Bibliographic Information

Other Title
  • D-β-Aspを特異的に認識する抗体を用いた扁桃等耳鼻科領域組織の免疫組織化学的検討
  • D-v-Asp オ トクイテキ ニ ニンシキ スル コウタイ オ モチイタ ヘントウ トウ ジビカ リョウイキ ソシキ ノ メンエキ ソシキ カガクテキ ケントウ

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Abstract

<p>  The protein contains D-beta-Asp (D-β-Asp protein) on palatine tonsils, nasal mucosa and vocal cords was investigated. The lymphoid follicles were mainly stained with an anti-D-β-Asp antibody increased with age in case of palatine tonsils. New finding of the existence of the D-β-Asp protein which spread around from the center to periphery was shown in the lymphoid follicles of the palatine tonsils of a 3 and a 11 years-old infants. The turnover time of lymphoid folliclesin nasal mucosa are so fast (about two weeks), then it is difficult to consider D-β-Asp proteins of lymphoid follicles are made during the long time exposure to UV, oxidant etc.</p><p>  The big difference to a staining pattern was not found in the palatine tonsils of a chronic tonsillitis and IgA nephropathy. From this point, D-β-Asp protein is not directly related to morbidity. Existence of D-β-Asp protein in lymphoid follicle of a child's palatine tonsil, and the D-β-Asp protein which is not directly related to morbidity was suggested.</p>

Journal

  • Viva Origino

    Viva Origino 40 (4), 57-61, 2012

    The Society for the Study of the Origin and Evolution of Life Japan

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