Regression of diffuse large B-cell lymphoma after discontinuation of salazosulfapyridine

DOI Web Site

Bibliographic Information

Other Title
  • Salazosulfapyridine中止を契機に消退したびまん性大細胞型B細胞リンパ腫
  • Salazosulfapyridine チュウシ オ ケイキ ニ ショウタイシタ ビマンセイ ダイ サイボウガタ Bサイボウ リンパシュ

Search this article

Abstract

<p>An 81-year-old man with a 3-year history of salazosulfapyridine (SASP) therapy for rheumatoid arthritis (RA) presented with pulmonary infiltrates and underwent computed tomography-guided biopsy. The histopathological and immunohistochemical evaluation confirmed the diagnosis of diffuse large B-cell lymphoma (DLBCL). He was recommended chemotherapy, which he refused. Due to the possibility of other iatrogenic immunodeficiency-associated lymphoproliferative disorders, SASP therapy was discontinued. SASP therapy withdrawal led to near-complete resolution of the lung infiltration shadows, and the serum soluble interleukin 2 receptor level returned to the normal range. This is the first report of a case of remission of DLBCL, following SASP therapy withdrawal in a patient with RA.</p>

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 63 (2), 99-103, 2022

    The Japanese Society of Hematology

Keywords

Details 詳細情報について

Report a problem

Back to top