A Case of Acute Onset Type 1 Diabetes Mellitus That Developed Three Months after Delivery With Depletion of Insulin Secretion from Just after the Onset

DOI

Bibliographic Information

Other Title
  • 出産3か月後に発症し，発症直後よりインスリン分泌の急速な低下を認めた急性発症1型糖尿病の1例

Description

<p>We herein report a patient with acute onset type 1 diabetes mellitus that developed three months after delivering a child with depletion of insulin secretion just after the onset. This patient was a 32-year-old woman who recognized excessive thirst, polydipsia, polyuria and digestive symptoms. She visited the emergency room in our hospital, and her laboratory findings showed that her blood glucose level was 664 mg/dL, HbA1c 9.7 %, urine ketone bodies (3+), venous blood gas pH 7.018, fasting-serum C peptide 0.41 ng/mL, and islet cell antibody (ICA) 20 JDF units. We diagnosed her with autoimmune acute-onset type 1 diabetes with diabetic ketoacidosis (DKA). Her HLA-typing was DRB1*04: 05-DQB1*04: 01, which indicates susceptibility to Japanese type 1 diabetes. Her insulin secretion further deteriorated and was almost completely lost just 10 days after the onset. We considered her beta cell destruction to have been accelerated after the onset of acute-onset type 1 diabetes (autoimmune).</p>

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Details 詳細情報について

  • CRID
    1390010292804728064
  • DOI
    10.11213/tonyobyo.65.90
  • ISSN
    1881588X
    0021437X
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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