Mortality Attributable to Carbapenem-Resistant Nosocomial Acinetobacter baumannii Infections in a Turkish University Hospital
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- Aydemir Hande
- Department of Infectious Diseases and Clinical Microbiology, Zonguldak Karaelmas University Medical Faculty, Turkey
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- Celebi Guven
- Department of Infectious Diseases and Clinical Microbiology, Zonguldak Karaelmas University Medical Faculty, Turkey
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- Piskin Nihal
- Department of Infectious Diseases and Clinical Microbiology, Zonguldak Karaelmas University Medical Faculty, Turkey
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- Oztoprak Nefise
- Department of Infectious Diseases and Clinical Microbiology, Zonguldak Karaelmas University Medical Faculty, Turkey
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- Keskin Aysegul Seremet
- Department of Infectious Diseases and Clinical Microbiology, Zonguldak Karaelmas University Medical Faculty, Turkey
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- Aktas Elif
- Department of Microbiology, Zonguldak Karaelmas University Medical Faculty, Turkey
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- Sumbuloglu Vildan
- Department of Biostatistics, Zonguldak Karaelmas University Medical Faculty, Turkey
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- Akduman Deniz
- Department of Infectious Diseases and Clinical Microbiology, Zonguldak Karaelmas University Medical Faculty, Turkey
書誌事項
- タイトル別名
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- Mortality Attributable to Carbapenem-Resistant Nosocomial <i>Acinetobacter baumannii</i> Infections in a Turkish University Hospital
この論文をさがす
抄録
<p>This study was performed to compare the mortality associated with carbapenem-resistant<tt> </tt>Acinetobacter baumannii<tt> </tt>(CRAB) and carbapenem sensitive<tt> </tt>A. baumannii<tt> </tt>(CSAB) infections, to identify potential risk factors for CRAB infections, and to investigate the effects of potential risk factors on mortality in CRAB and CSAB patients. This retrospective case-control study was conducted in a university hospital between January 1, 2005 and December 30, 2006. One hundred and ten patients with CRAB and 55 patients with CSAB infection were identified during the study period. The mortality rate was 61.8% and 52.7% in CRAB and CSAB cases, respectively (P<tt> </tt>= 0.341). In CRAB cases, the risk factors for mortality were identified as intubation (odds ratio [OR], 3.3; 95% confidence interval [CI], 1.0–10.1;<tt> </tt>P<tt> </tt>= 0.042) and high APACHE II score (OR, 1.2; 95% CI, 1.1–1.3;<tt> </tt>P<tt> </tt>= 0.000), by multivariate analysis. Previous use of carbapenem (OR, 6.1; 95% CI, 2.2–17.1;<tt> </tt>P<tt> </tt>= 0.001) or aminopenicillin (OR, 2.5; 95% CI, 1.2–5.1;<tt> </tt>P<tt> </tt>= 0.013) were independently associated with carbapenem resistance. Although the mortality rate was higher among patients with CRAB infections, this difference was not found to be statistically significant. Previous use of carbapenem and aminopenicillin were found to be independent risk factors for infections with CRAB.</p>
収録刊行物
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- Japanese Journal of Infectious Diseases
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Japanese Journal of Infectious Diseases 65 (1), 66-71, 2012-01-31
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
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詳細情報 詳細情報について
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- CRID
- 1390010292831780608
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- NII論文ID
- 40019139492
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- NII書誌ID
- AA1132885X
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- ISSN
- 18842836
- 13446304
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- NDL書誌ID
- 023392343
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可