A Case of IgG4-related Pleuritis Diagnosed with Pleural Biopsy via Thoracoscopy Under Local Anesthesia
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- Sekiguchi Ryo
- Department of Respiratory Medicine, Toho University School of Medicine
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- Nakamura Yasuhiko
- Department of Respiratory Medicine, Toho University School of Medicine
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- Motohashi Takumi
- Department of Respiratory Medicine, Toho University School of Medicine
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- Urabe Naohisa
- Department of Respiratory Medicine, Toho University School of Medicine
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- Ishiki Takuma
- Department of Respiratory Medicine, Toho University School of Medicine
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- Isobe Kazutoshi
- Department of Respiratory Medicine, Toho University School of Medicine
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- Sakamoto Susumu
- Department of Respiratory Medicine, Toho University School of Medicine
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- Takai Yujiro
- Department of Respiratory Medicine, Toho University School of Medicine
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- Homma Sakae
- Department of Advanced and Integrated Interstitial Lung Disease Research, Toho University School of Medicine
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- Kishi Kazuma
- Department of Respiratory Medicine, Toho University School of Medicine
Bibliographic Information
- Other Title
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- 局所麻酔下胸腔鏡検査による胸膜生検で診断したIgG4関連胸膜炎の1例
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Description
<p>Background. Immunoglobulin (Ig) G4-related disease is characterized by the infiltration of IgG4-positive plasma cells into various organs. A pathological diagnosis based on bronchoscopic or surgical biopsy is required for the definitive diagnosis of IgG4-related respiratory disease. Case Presentation. An 82-year-old man with a 15-year history of hypergammaglobulinemia was examined for bilateral pleural effusion that had been unresponsive to diuretics for approximately half a year. IgG and IgG4 levels in the blood and IgG levels in the pleural effusion were elevated, and thoracoscopy was performed under local anesthesia. A pleural biopsy of the dark brown lesion was performed. The biopsy specimen revealed the infiltration of IgG4-positive plasma cells into the tissue, leading to a diagnosis of IgG4-related pleuritis. The patient was thus treated with prednisolone, and the pleural effusion improved. Conclusion. A pleural biopsy via thoracoscopy under local anesthesia is useful for diagnosing of IgG4-related pleuritis and should be considered if the disease is suspected.</p>
Journal
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- The Journal of the Japan Society for Respiratory Endoscopy
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The Journal of the Japan Society for Respiratory Endoscopy 44 (2), 153-159, 2022-03-25
The Japan Society for Respiratory Endoscopy
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Keywords
Details 詳細情報について
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- CRID
- 1390010292885837696
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- ISSN
- 21860149
- 02872137
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- Text Lang
- ja
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- Data Source
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- JaLC
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- Abstract License Flag
- Disallowed