肥満小児に合併しやすい脂質異常症

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  • Dyslipidemia, a common complication in obese children
  • ヒマン ショウニ ニ ガッペイ シヤスイ シシツ イジョウショウ

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Obese children suffer from a variety of complications. Among them, dyslipidemia is one of the most common complications. There are gender and age differences in serum TC and HDL-C levels in children. And as obesity becomes more severe, the lipid profile tends to be more atherosclerosis-inducing. Therefore, obesity treatment from childhood and correction of dyslipidemia associated with obesity are necessary for the primary prevention of cardiovascular disease. Since the diagnostic criteria for dyslipidemia differ between adults and children, it is necessary to use the diagnostic criteria for children. There are two types of dyslipidemia: primary dyslipidemia and secondary dyslipidemia, specifically, hyper-LDL-cholesterolemia, hypertriglyceridemia, and hypo-HDL-cholesterolemia. Familial hypercholesterolemia（ FH） is the most common cause of primary hyperlipidemia, but many cases of FH are not associated with obesity. On the other hand, secondary dyslipidemias that tend to be associated with obesity are hypertriglyceridemia and hypo-HDL-cholesterolemia. The treatment of these dyslipidemias is to correct excessive intake of simple sugars and carbohydrates, and to actively consume n-3 polyunsaturated fatty acids. For hypo-HDL-cholesterolemia, exercise is recommended in addition to dietary guidance.

収録刊行物

  • 脂質栄養学

    脂質栄養学 31 (1), 36-44, 2022-03-31

    日本脂質栄養学会

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