Effectiveness of Spinal Instability Neoplastic Score to Detect the Risk of Neurological Deficit in Patients with Spinal Metastasis

DOI
  • Yamamoto Masatoshi
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University
  • Iida Keiichiro
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University
  • Kobayakawa Kazu
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University
  • Nabeshima Akira
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University
  • Fujiwara Toshifumi
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University
  • Saiwai Hirokazu
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University
  • Endo Makoto
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University
  • Kawaguchi Kenichi
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University
  • Matsumoto Yoshihiro
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University
  • Nakashima Yasuharu
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University

Bibliographic Information

Other Title
  • 転移性脊椎腫瘍による脊髄症状リスク患者検出に対するSpinal Instability Neoplastic Scoreの有効性についての検討

Search this article

Description

<p>Introduction: The spinal instability neoplastic score (SINS) is a classification system used to diagnose neoplastic spinal instability. Several reports have also described its use as a screening tool to identify patients at risk of skeletal-related events. We investigated the efficacy of SINS to detect the risk of neurological deficit in patients with spinal metastases by assessing spinal metastatic instability before the onset of myelopathy.</p><p>Methods: We performed surgery on 81 patients with cervical or thoracic lesions classified as metastatic spine disease between 2004 and 2019. In this cohort, spinal instability was assessed in 29/81 patients before the occurrence of myelopathy. Spinal instability was evaluated by SINS with computed tomography (CT) performed within 6 months of the neurological deficit. We defined patients with a score of 7 or higher as at-risk patients.</p><p>Results: CT was performed at an average of 72 days before the onset of neurological deficits. The SINS were 2 no-metastases cases, 4 of less than 7 (stability), 15 of 7-12 (indeterminate instability), and 8 of 13-18 (instability). We were unable to detect 21% (6/29) patients at risk of SINS.</p><p>Conclusions: We may not be able to detect approximately 20% at-risk patients with neurological deficits by SINS before myelopathy presents.</p>

Journal

  • Journal of Spine Research

    Journal of Spine Research 14 (2), 82-87, 2023-02-20

    The Japanese Society for Spine Surgery and Related Research

Keywords

Details 詳細情報について

Report a problem

Back to top