Survey of Magnesium Oxide Tablet Usage in Japan Using NDB Open Data
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- Ishimura Atsushi
- Division of Practical Pharmacy, Nihon Pharmaceutical University
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- Shimizu Yutaka
- Pharmaceutical department, Sainokumi Higashiomiya Medical Center
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- Onishi Ayano
- Division of Practical Pharmacy, Nihon Pharmaceutical University
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- Yabuki Naohiro
- Pharmaceutical department, Sainokumi Higashiomiya Medical Center
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- Matsuda Yoshikazu
- Division of Practical Pharmacy, Nihon Pharmaceutical University
抄録
Magnesium oxide, a low-price laxative without a habit-forming tendency after long-term use, is widely used for treating constipation in Japan. However, its use has been associated with hypermagnesemia in patients with impaired magnesium excretion function such as renal insufficiency. Therefore, in this study, we investigated the use of magnesium oxide tablets, which may be administered to the elderly on a long-term basis. We found the total number of prescriptions has increased year by year and exceeded 4 billion tablets in FY 2020. The use and number of prescriptions were highest among individuals in their 80s, and more than 70% of patients taking the drug are aged 70 years or older. Since the elderly experience physiological functional decline, pharmacists must make effective use of not only age but also laboratory data listed on prescriptions when dispensing these medications in order to prevent adverse events.
収録刊行物
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- アプライド・セラピューティクス
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アプライド・セラピューティクス 18 (0), 16-21, 2023
日本アプライド・セラピューティクス(実践薬物治療)学会
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詳細情報 詳細情報について
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- CRID
- 1390014648121435264
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- ISSN
- 24329185
- 18844278
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- 抄録ライセンスフラグ
- 使用不可